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65f · Named for 65°F, the temperature of better sleep

Wellness, with citations.

65f is a peer-driven wellness archive: every claim has a source, every page has its own discussion, and every contribution is part of one connected forum. The name is a nod to the temperature sleep scientists cite as optimal — small numbers, done right.

Peptides
69
Magazine
24
Pillars
7
Threads
20

The seven pillars

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From the magazine

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Exercise May Rewire Heart's Nerves Asymmetrically, Potentially Leading to Targeted Therapies

New research suggests that regular moderate aerobic exercise not only strengthens the heart but also reshapes its nerve network in a side-specific manner. This discovery could pave the way for more personalized treatments for various heart conditions.

4 minpreclinical

New Research Highlights Sleep's Impact on Immunity, Narcolepsy Mechanisms, and Sleep Apnea Detection

Recent studies in Nature Portfolio journals explore diverse aspects of sleep disorders, including the link between poor sleep and weakened immune responses, novel insights into narcolepsy, and advancements in non-contact sleep apnea detection. The research underscores sleep's critical role in overall health and identifies potential new therapeutic targets and diagnostic tools.

4 minearly clinical

Sleep-Aligned Fasting May Support Overnight Heart Health, Early Study Suggests

New research indicates that aligning an overnight fast with the body's natural sleep cycle, by stopping food intake several hours before bed, could positively influence cardiovascular health during sleep. This approach, termed "sleep-aligned eating," suggests that the timing of meals, not just what is eaten, plays a crucial role in heart health.

3 min

Sleep Apnea's Gut-Heart Connection: A New Avenue for Cardiovascular Disease Prevention

New research suggests a surprising link between sleep apnea, gut health, and heart disease. Disabling a specific bile acid receptor in mice significantly reduced plaque buildup, offering a potential new therapeutic target.

3 min

Psychedelic Treatment Luvesilocin Shows Promise for Postpartum Depression and Anxiety

A new psychedelic compound, luvesilocin, is undergoing FDA clinical trials for postpartum depression and anxiety, showing promising results in early studies. This treatment could offer a novel approach to conditions affecting nearly 20% of new mothers.

3 min

New Research Uncovers Molecular Mechanism Behind Exercise's Anti-Aging Effects on Muscles

Scientists have identified a molecular "switch" that helps explain how exercise maintains muscle health and strength in older age. This discovery sheds light on the biological processes that contribute to age-related muscle decline and how physical activity can counteract them.

3 min

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