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65f · Named for 65°F, the temperature of better sleep

Wellness, with citations.

65f is a peer-driven wellness archive: every claim has a source, every page has its own discussion, and every contribution is part of one connected forum. The name is a nod to the temperature sleep scientists cite as optimal — small numbers, done right.

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The seven pillars

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From the magazine

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Cellular Memory Suggests Exercise Benefits Persist Even After Training Breaks

New research indicates that cells in various organs, including muscles and the liver, retain a 'memory' of past exercise. This cellular record may help the body regain fitness faster after a break and offers benefits like improved endurance and blood sugar control, challenging the traditional 'use it or lose it' notion [1].

3 min

Exercise Timing and Sleep: Morning vs. Evening Workouts Show Similar Benefits

A recent meta-analysis explored whether the time of day exercise is performed impacts sleep quality, finding that morning and evening workouts generally offer comparable sleep benefits. However, evening exercise might lead to slightly increased sleep disturbances in some individuals [1].

5 minearly clinical

Semaglutide Shows Potential to Slow Aging and Extend Lifespan in Female Mice

New research in mice suggests that semaglutide, a GLP-1 receptor agonist, may offer benefits beyond its known effects on diabetes and weight loss, potentially influencing the aging process and lifespan.

4 minpreclinical

AI-Powered Knowledge Graph Unravels Complex Mechanisms of Aging and Longevity

Researchers have developed an AI-driven knowledge graph, HALDxAI, to integrate vast amounts of scientific literature and biomedical data, offering a systems-level understanding of aging and longevity mechanisms. This tool aims to reduce knowledge fragmentation and facilitate new discoveries in anti-aging interventions.

6 minpreclinical

NIH Panel Identifies Research Priorities for Improving Health During Menopausal Transition

A recent workshop organized by the National Institutes of Health (NIH) has led to a draft report outlining critical research priorities to enhance health outcomes during the menopausal transition. This initiative aims to address current gaps in understanding and managing this significant life stage.

4 minpreclinical

Creatine Supplementation Shows Promise for Muscle and Strength Gains, Even Without Exercise

New research suggests that creatine may help middle-aged adults increase lean tissue and strength, even in the absence of a structured exercise program. When combined with exercise and a calorie-reduced diet, it further enhances strength and aids in fat loss while preserving muscle.

4 minearly clinical

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