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Hormones & Longevity

HRT, TRT, metabolic & longevity

Endocrine health, metabolic markers, and protocols at the frontier of longevity medicine.

From the magazine · 5

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Menopause and Hormone Use Linked to Bladder Health and Lower Urinary Tract Symptoms

A recent study indicates that women in perimenopause and postmenopause experience worse bladder health and more lower urinary tract symptoms compared to premenopausal women. Hormone use, particularly in postmenopausal women, was also associated with poorer bladder health outcomes.

4 min read· early clinical· 7/4/2026

The Impact of Exercise on Cognitive Function and Brain Health: A Review of Current Evidence

Regular physical activity has been consistently linked to improved cognitive function and a reduced risk of neurodegenerative diseases. This review synthesizes current research on how exercise influences brain health across different life stages.

5 min read· established· 6/24/2026

Testosterone Therapy in Men: Who It’s For—and What It Might Cost

Testosterone therapy can be transformative for men with true hypogonadism, but its role in age-related low T is far less clear. Here’s what the evidence says about indications, benefits, and real-world risks.

11 min read· early clinical· 6/19/2026

Menopause hormone therapy: what the modern evidence really shows

Once vilified, menopausal hormone therapy is being reconsidered through a more nuanced, data-driven lens. Here’s what contemporary evidence says about benefits, risks, and who is most likely to gain from treatment.

10 min read· established· 6/19/2026

GLP‑1 drugs beyond weight loss: what longevity science is really finding

GLP‑1 receptor agonists are now marketed as weight‑loss blockbusters, but emerging data suggest broader cardiometabolic, kidney, liver, and brain effects that may matter for healthy longevity—alongside real uncertainties and risks.

10 min read· early clinical· 6/19/2026