SCFA, Where They Go

Summary

Fiber-fermenting bacteria produce three dominant SCFAs in roughly fixed molar ratios. Each has a distinct end-organ.

Takeaway

Butyrate is the colon's primary fuel and an HDAC inhibitor — central to barrier integrity.

Citations · 1

1. [01]
   Koh A et al. (2016). From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites. Cell. doi:10.1016/j.cell.2016.05.041
   Source